Irritable Bowel syndrome

What is Irritable Bowel Syndrome?

Imagine your stomach and intestines as a busy train station. The trains (food) are supposed to pass through smoothly on schedule. But in Irritable Bowel Syndrome (IBS), the trains either rush too fast (causing diarrhea), crawl slowly (causing constipation), or stop randomly and make everyone uncomfortable (causing gas, pain, or bloating).

IBS isn’t like a broken bone that can be seen in an X-ray. It’s a functional disorder, which means the system doesn’t work right, but nothing shows up as damaged. It’s your gut miscommunicating with your brain. This misunderstanding causes the bowel to overreact to things like stress, certain foods, or even hormones.

IBS doesn’t cause permanent harm or increase cancer risk. But it can really mess with daily life. That’s why it’s one of the most commonly talked-about conditions in gut-brain research and gastrointestinal problems.

What are the Types of IBS?

There isn’t just one version of IBS. It’s more like different moods of the same gut:

IBS with Diarrhea (IBS-D)

IBS with Diarrhea (IBS-D)

The intestines move too fast. You feel urgency, loose stools, and stomach cramps. Example: You eat something mild and find yourself rushing to the toilet multiple times a day.

IBS with Constipation (IBS-C)

IBS with Constipation (IBS-C)

The intestines move too slowly. You feel bloated, uncomfortable, and like nothing is "moving." Example: Even with fiber, you might go for days without relief.

Mixed IBS (IBS-M)

Mixed IBS (IBS-M)

Some days, it’s constipation. Other days, diarrhea. And no clear reason why. Example: It’s like the weather in your stomach keeps changing without warning.

These different types help doctors figure out the treatment for irritable bowel syndrome that suits your body best.

What are the Signs & Symptoms of IBS?

Here’s how it usually shows up:

Bloating – Your stomach feels like a balloon.

Bloating – Your stomach feels like a balloon.

Stomach pain

Stomach pain or cramps, often better after going to the toilet.

Gas

Gas – Sometimes embarrassing, but very common.

Diarrhea

Diarrhea or constipation (or both at different times)

Mucus in stool

Mucus in stool – a slippery coating that's not usually there

Tiredness, anxiety

Tiredness, anxiety, or poor concentration, especially on bad gut days

These aren’t “just tummy issues.” IBS often comes with mood swings, irritability, and a sense that something’s always off. That’s why it’s being explored more in gut-brain connection and gut microbiome studies.

What Causes IBS?

There’s no one villain behind IBS—it’s more like a team of tricky suspects working together:

  • Gut-Brain Communication Problems
  • Gut Dysbiosis
  • Stress and Emotions
  • Food Triggers
  • Genetics and Past Infections

Your brain and gut constantly talk to each other. When that communication is off, your gut may overreact. This is a central idea in the autism gut-brain axis, too.

Gut-Brain Communication Problems

That’s when the “good” bacteria in your gut are outnumbered by the “bad” ones. Gut dysbiosis can trigger bloating, pain, and even affect mood.

Gut Dysbiosis

IBS often worsens with anxiety, nervousness, or tension. Some even call the gut a "second brain."

Stress and Emotions

Spicy foods, dairy, gluten, caffeine, and fried food are common triggers. But it’s different for each person.

Food Triggers

If a family member has IBS, or if you had a tough gut infection before, your chances go up.

Genetics and Past Infections
  • Gut-Brain Communication Problems
  • Gut Dysbiosis
  • Stress and Emotions
  • Food Triggers
  • Genetics and Past Infections

Your brain and gut constantly talk to each other. When that communication is off, your gut may overreact. This is a central idea in the autism gut-brain axis, too.

Gut-Brain Communication Problems

That’s when the “good” bacteria in your gut are outnumbered by the “bad” ones. Gut dysbiosis can trigger bloating, pain, and even affect mood.

Gut Dysbiosis

IBS often worsens with anxiety, nervousness, or tension. Some even call the gut a "second brain."

Stress and Emotions

Spicy foods, dairy, gluten, caffeine, and fried food are common triggers. But it’s different for each person.

Food Triggers

If a family member has IBS, or if you had a tough gut infection before, your chances go up.

Genetics and Past Infections

What Tests Find IBS?

There’s no one test to say “yes, this is IBS.” Doctors figure it out by ruling out other problems.

Medical History

Medical History

They’ll ask about symptoms, triggers, and patterns—especially if it’s lasted more than 3 months.

Blood and Stool Tests

Blood and Stool Tests

These help rule out infections, celiac disease, or inflammation (like in Crohn’s disease).

Colonoscopy or Imaging

Colonoscopy or Imaging

Only used if symptoms are serious or if there are red flags like weight loss or bleeding.

Gut Microbiome Test

Gut Microbiome Test

Sometimes doctors recommend a gut microbiome test to look at bacterial balance, especially when exploring gut issues in autism or functional gut disorders.

How Common is IBS?

IBS affects about 10–15% of people worldwide. That’s more than 1 in every 10 people.

It’s more common in:

  • Teenagers and young adults
  • Girls more than boys
  • People with anxiety or emotional sensitivity

 

In places like India, IBS often goes undiagnosed or mislabelled as “gas trouble” or “stress.” But awareness is growing, especially with the popularity of gut microbiome research and FMT for irritable bowel syndrome.

Alternate and Newer Treatments

  • Ayurveda – focuses on gut balance with herbal oils, detox routines, and special diets.

  • Homeopathy – may be used for bloating, gut sensitivity, or mood issues.

  • Probiotics – help restore good bacteria, though their effects vary.

  • FMT / GMT – reshaping gut flora directly.

  • Functional Medicine – treating IBS by looking at the whole body: food, hormones, sleep, emotions.

  • Biofeedback – helps people become aware of gut tension and manage symptoms better.

  • Gut-Brain Axis Therapy – exploring how mood, thought, and stress affect digestion, especially in autism spectrum disorder treatment or child development centers.

IBS doesn’t show up in scans or leave scars, but it changes how you eat, sleep, study, and even socialize. It whispers through the gut, sometimes screams. But the more you listen, learn, and treat it with care, the more peace your body—and your brain—can find.

How Does Gut Microbiota Transplantation (GMT/FMT) Help with IBS?

At Resplice Research Institute, doctors are using Gut Microbiota Transplantation (GMT) to help people with Irritable Bowel Syndrome (IBS)—especially those who deal with stubborn constipation, unpredictable diarrhea, painful bloating, gas, and brain fog that often comes with it.

The Big Idea: Fix the Gut, Calm the Storm

Think of your gut like a city full of tiny workers, bacteria that help digest food, manage inflammation, and even send messages to your brain about how you feel. In people with IBS, this city is often out of balance. Some of the workers have gone rogue, and the good ones aren’t strong enough to keep the peace. This is called gut dysbiosis, and it plays a huge role in how IBS symptoms appear and persist.

GMT works by gently introducing helpful bacteria from the poop of a healthy child (called a donor) into the gut of the person with IBS. It’s like replanting a garden: you remove the weeds, bring in fresh soil, and let new life grow. Over time, these “good” microbes settle in, crowd out the harmful ones, and bring the gut back into balance.

Resplice Outcome in IBS:

What Makes GMT at Resplice Different and Safe?

  1. Global Standard Donor Screening: Not just any healthy kid can donate. Resplice uses a strict screening process based on the International Stool Banking Consensus, along with gut microbiome tests. This includes:
    • Testing for bad germs (bacteria, viruses, parasites)
    • Ensuring no chronic illnesses are present
    • Food intolerance testing to match the donor’s gut health to the needs of the IBS recipient
    • Only children with the cleanest, most balanced gut flora are selected.

 

  1. Why Use Children as Donors, Not Adults? Most centers use adult donors. Resplice doesn’t. Why?
    •     Children’s guts are less exposed to pollution, junk food, and chemicals
    •     Their gut bacteria are still in a “natural” state—cleaner and more suited for healing
    •     Adult microbiomes may be more diverse, but often carry toxins or hidden imbalances
    •     That’s why child donors offer a gentler, safer, and purer microbiome for people with IBS.

 

  1. Collection & Processing – Ultra-Hygienic
    • Fresh stool is collected in gamma-sterilized containers
    • It’s kept cold (4°C) during transport to preserve good bacteria
    • Microscopy tests check for unwanted organisms
    • The sample is blended, spun at high speed (refrigerated centrifugation), and only the clear liquid (supernatant) is used
    • This is delivered via colonic infusion—a clean, gentle method to place good bacteria directly into the large intestine
    • Everything is handled like a scientific operation, with zero room for contamination.

 

  1. It’s a Journey, Not a One-Time Fix: You can’t rebuild a city overnight. The same goes for your gut. GMT at Resplice is done in multiple rounds over several weeks. Each infusion gives the gut new helpers, helping them settle, multiply, and slowly push out the bad ones. As the balance improves, people with IBS often report:
    • Reduced bloating and discomfort
    • More regular and pain-free bowel movements
    • Fewer flare-ups after meals
    • Clearer thinking and better sleep
    • A calmer, more stable mood

 

It doesn’t turn your gut into someone else’s—it simply helps your own body return to its natural rhythm by rebalancing what went wrong inside.

At Resplice, GMT for IBS is backed by science, handled with compassion, and always paired with diet advice, emotional support, and therapies as part of a bigger healing plan. It’s not about replacing medicines, but about giving your gut the support it needs to find peace again.

Frequently Asked Questions (FAQs) About IBS

1. What is Irritable Bowel Syndrome (IBS)?

IBS is a common gut disorder where your stomach and intestines don’t work quite right. It causes cramping, bloating, gas, diarrhea, or constipation. It’s not dangerous, but it can be disruptive and uncomfortable.

2. How is IBS different from other digestive disorders?

IBS doesn’t damage the gut like ulcers or Crohn’s disease. It’s a functional problem—your gut miscommunicates with your brain, so symptoms happen even when tests come back normal.

3. What are the types of IBS?

There are three types:

IBS-D: Mostly diarrhea
IBS-C: Mostly constipation

IBS-M: Mixed pattern of both
Knowing your type helps doctors tailor your treatment.

4. What causes IBS?

IBS can be caused by a mix of things: poor gut-brain communication, stress, gut dysbiosis (imbalance in gut bacteria), food triggers, past infections, or even genetics. Often, no single cause can be pinpointed.

5. What are the early signs of IBS?

Symptoms include gas, bloating, stomach cramps, irregular bowel movements (too often or not enough), mucus in stools, fatigue, and sometimes brain fog or anxiety.

6. Is IBS linked to mental health?

Yes. IBS is closely connected to stress, anxiety, and emotions via the gut-brain axis. Emotional changes can worsen IBS symptoms and vice versa.

7. How is IBS diagnosed?

There’s no single test. Doctors use your history, rule out other diseases, and sometimes order stool tests, blood work, or a colonoscopy if needed.

8. Is IBS curable?

There’s no one-time cure, but many people manage it well with a mix of diet changes, stress management, therapy, and—in some cases—microbiome-based treatments like GMT.

9. What foods should I avoid with IBS?

Common triggers include dairy, gluten, fried foods, caffeine, spicy meals, and artificial sweeteners. But it’s different for everyone. Keeping a food diary helps identify your personal triggers.

10. What is Gut Microbiota Transplantation (GMT), and how can it help IBS?

GMT involves transferring healthy bacteria from a child donor’s stool into the IBS patient’s gut. At Resplice, this helps restore microbial balance, calm symptoms, and support gut-brain communication.

11. Why does Resplice use child donors for GMT?

Child donors have cleaner, less polluted microbiomes. Their gut bacteria are closer to nature, with fewer chemical exposures. This makes the transplant gentler and potentially more effective.

12. Is GMT safe?

At Resplice, yes. They follow international screening standards, use sterile containers, test for infections, and use a cold-processing method to preserve good bacteria. Only the safest, cleanest samples are used.

13. How long does GMT treatment take?

GMT is done over several sessions. It’s not a one-time fix—it takes weeks for the new gut bacteria to settle and start changing the IBS symptoms. Most patients notice gradual improvement.

14. What other therapies are available for IBS?

Beyond GMT, IBS management may include Ayurveda, homeopathy, probiotics, biofeedback, functional medicine, and gut-brain therapy. Each works differently, and many people combine them for the best outcome.

15. Can IBS be connected to autism or child development issues?

Yes. Children with autism often show signs of IBS or gut sensitivity. Therapies like GMT and gut-brain axis treatment are used in both IBS and autism-related care at places like Resplice.